Two Sides of a Coin:
Deletions and Duplications on 15q
Angelman Syndrome Foundation and Dup15q Alliance Scientific Symposium
July 28 – 29, 2016
Sheraton Silver Spring Hotel in Silver Spring, MD.
At the Symposium, researchers and clinicians present their latest discoveries and share ideas for future projects. Watch individual recordings below or from the Scientific Symposium YouTube playlist. (More videos to come as they are available.)
Ovid: Towards Improved Outcomes in Rare Neurodevelopemntal Disorders Via Targeted Treament.
Brett Abrahams, Ph.D., Director of Pre-Clinical Biology at Ovid Therapeutics
Gene Reviews Overview of Dup15q, AS & the Critical Region.
Joint session: Stormy Chamberlain, Ph.D., UConn; Ron Thibert, D.O., MassGeneral Hospital; Shafali Jeste, M.D., UCLA
Cannabidiol for Epilepsy.
Orrin Devinsky, M.D., NYU Langone’s Comprehensive Epilepsy Center
Dendritic Spine Development in Dup15q and AS.
Les Loew, Ph.D., UConn School of Medicine
Sleep in Angelman & Dup15q.
Joint session: Ron Thibert, D.O., MassGeneral Hospital; Shafali Jeste, M.D., UCLA
Symposium Summary: Next Steps for Dup15q/Angelman Syndrome Research
Larry Reiter, Ph.D., University of Tennessee Health Science Center
Hurdles to be Overcome for a Trail of Oligonucleotide Therapy in AS.
Art Beaudet, M.D., Baylor College of Medicine
Biomarkers for Clinical Studies of Angelman Syndrome.
Art Beaudet, M.D., Baylor College of Medicine
Thursday, July 28
7:00 am Breakfast
8:00 am
Welcoming Remarks: Guy Clavert and Dan Harvey
8:15 am
GeneReviews overview of dup15q syndrome, AS, and the critical region: Stormy Chamberlain | Ron Thibert | Shafali Jeste
8:45 am
Insights from research in other syndromes (Christianson): Eric Morrow
9:30 am BREAK
10:00 am
dup15q fellowship update #1: Kevin Hope | dup15q fellowship update #2: James Fink
11:00 am BREAK
11:30 am
UCLA mouse studies: Peyman Golshani
12:00 pm
TBD: Ben Philpot
12:30 pm LUNCH BREAK
1:30 pm
CT stem cells intro/overview/core updates: Stormy Chamberlain
2:00 pm
CT stem cells #2; morphology: Les Loew
2:30 pm
stem cells #3; electrophysiology: Eric Levine
3:00 pm BREAK
3:20 pm
Autism Brain Net: Alycia Halladay
3:30 – 5:00 Breakout Sessions
AS Breakout Room: Levodopa in Angelman Syndrome – Results of a Multicenter Randomized Controlled Trial: Wen Han
dup15q Breakout Room: Update on dup15q mouse project: Scott Dindot | Behavioral characterization of dup15q mice: Jill Silverman
Friday, July 29
8:00 am
CBD: Orrin Devinsky
8:45 am
UBE3A: Martin Scheffner
9:30 am BREAK
10:00 am
TBD: David Segal
10:30 am
TBD: Mark Zylka
11:00 am BREAK
11: 30 am
Ionis – ASOs: Art Beaudet
12:00 pm
Agilis Biotherapeutics: Ed Weeber
12:30 pm LUNCH BREAK
1:00 pm
Phenotyping, quant EEG: Shafali Jeste
1:30 pm
Sleep data (overview for dev disorders generally and 15q/AS in particular): Ron Thibert | Shafali Jeste
2:00 pm BREAK
2:30 pm
Ovid: Brett Abrahams
3:00 pm
DPSC methylome data: Janine LaSalle
3:30 pm BREAK
4:00 – 5:00 pm
Next steps for dup15q/AS research