Two Sides of a Coin:
Deletions and Duplications on 15q

Angelman Syndrome Foundation and Dup15q Alliance Scientific Symposium
July 28 – 29, 2016
Sheraton Silver Spring Hotel in Silver Spring, MD.

At the Symposium, researchers and clinicians present their latest discoveries and share ideas for future projects. Watch individual recordings below or from the Scientific Symposium YouTube playlist. (More videos to come as they are available.)

Ovid: Towards Improved Outcomes in Rare Neurodevelopemntal Disorders Via Targeted Treament.
Brett Abrahams, Ph.D., Director of Pre-Clinical Biology at Ovid Therapeutics

Gene Reviews Overview of Dup15q, AS & the Critical Region.
Joint session: Stormy Chamberlain, Ph.D., UConn; Ron Thibert, D.O., MassGeneral Hospital; Shafali Jeste, M.D., UCLA

Cannabidiol for Epilepsy.
Orrin Devinsky, M.D., NYU Langone’s Comprehensive Epilepsy Center

Dendritic Spine Development in Dup15q and AS.
Les Loew, Ph.D., UConn School of Medicine

Sleep in Angelman & Dup15q.
Joint session: Ron Thibert, D.O., MassGeneral Hospital; Shafali Jeste, M.D., UCLA

Symposium Summary: Next Steps for Dup15q/Angelman Syndrome Research
Larry Reiter, Ph.D., University of Tennessee Health Science Center

Hurdles to be Overcome for a Trail of Oligonucleotide Therapy in AS.
Art Beaudet, M.D., Baylor College of Medicine

Biomarkers for Clinical Studies of Angelman Syndrome.
Art Beaudet, M.D., Baylor College of Medicine

Thursday, July 28

7:00 am  Breakfast

8:00 am
Welcoming Remarks: Guy Clavert and Dan Harvey

8:15 am
GeneReviews overview of dup15q syndrome, AS, and the critical region: Stormy Chamberlain | Ron Thibert | Shafali Jeste

8:45 am
Insights from research in other syndromes (Christianson): Eric Morrow

9:30 am  BREAK

10:00 am
dup15q fellowship update #1:  Kevin Hope  | dup15q fellowship update #2:  James Fink

11:00 am  BREAK

11:30 am
UCLA mouse studies: Peyman Golshani

12:00 pm
TBD: Ben Philpot

12:30 pm   LUNCH BREAK

1:30 pm
CT stem cells intro/overview/core updates: Stormy Chamberlain

2:00 pm
CT stem cells #2; morphology: Les Loew

2:30 pm
stem cells #3; electrophysiology: Eric Levine

3:00 pm  BREAK

3:20 pm
Autism Brain Net: Alycia Halladay

3:30 – 5:00 Breakout Sessions
AS Breakout Room: Levodopa in Angelman Syndrome – Results of a Multicenter Randomized Controlled Trial:  Wen Han
dup15q Breakout Room: Update on dup15q mouse project: Scott Dindot  |   Behavioral characterization of dup15q mice: Jill Silverman


 

Friday, July 29

8:00 am
CBD: Orrin Devinsky

8:45 am
UBE3A: Martin Scheffner

9:30 am  BREAK

10:00 am
TBD: David Segal

10:30 am
TBD: Mark Zylka

11:00 am  BREAK

11: 30 am
Ionis – ASOs: Art Beaudet

12:00 pm
Agilis Biotherapeutics: Ed Weeber

12:30 pm  LUNCH BREAK

1:00 pm
Phenotyping, quant EEG: Shafali Jeste

1:30 pm
Sleep data (overview for dev disorders generally and 15q/AS in particular): Ron Thibert | Shafali Jeste

2:00 pm  BREAK

2:30 pm
Ovid: Brett Abrahams

3:00 pm
DPSC methylome data: Janine LaSalle

3:30 pm   BREAK

4:00 – 5:00 pm
Next steps for dup15q/AS research