Charlotte DiStefano, PhD
June 24, 2020

EEG Biomarkers of Language in Angelman Syndrome

$200,000 The goal of this study is to establish biomarkers of language function in Angelman syndrome. Language is a likely target for both behavioral and pharmaceutical treatment, as it represents a core deficit in Angelman syndrome and is a major […]

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Dr. Joseph Wagstaff
January 23, 2020

Melatonin and Sleep in Angelman Syndrome

$10,000 This research grant determined if melatonin, a well-known drug that has been used to improve sleep, could be effective in individuals with Angelman syndrome (AS). Children with AS were monitored at night using motion detecting devices and sleep observations. […]

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January 23, 2020

GABA beta3 Deficient Mice

$10,000 The gene that is defective in AS is UBE3A and in 70% of individuals who have AS this gene and genes nearby it are deleted from chromosome 15. This project sought to determine if one of the adjacent genes […]

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Dr. Henriette Moll
January 23, 2020

CompAS

The aim of this study is to quantify the effect on communicative abilities of participants* with Angelman syndrome (AS) of high intensity and low intensity training of parents and caretakers in Augmentative and Alternative Communication (AAC). Parents will be taught […]

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