$3,213 This research project was one of the earliest extensive surveys of behavioral traits in AS and was funded and enabled by the Angelman Syndrome Foundation (ASF) because of ASF’s affiliation with so many families within and outside of the […]
Read more
$10,581 Individuals with AS are quite animated in their attempts at communication and can be pro-social even though they have severe speech impairment. Although fluent sign language is beyond the motor and cognitive abilities of those with AS, there is […]
Read more
$62,903 One of the unique aspects of the brain problem in AS is that only the UBE3A on the maternally inherited number 15 chromosome is disrupted. The other UBE3A, located on the paternally derived chromosome, is silenced by a control […]
Read more
$25,000 UBE3A, the gene when disrupted causes AS, is present in all animal and insect species, thus indicating how important it is for normal neuronal function. These investigators were able to identify the equivalent of the UBE3A gene in Drosophila, […]
Read more$3,600 ASF maintains contact with hundreds of families throughout the United States and in other parts of the world and this contact serves as a valuable resource for investigators wishing to learn more about certain behavioral or medical problems of […]
Read more$29,700 Visual media plays a powerful role in helping families and others understand the natural history and many of the day-to-day concerns that parents have for their children and adults with AS. This work combines the skills of individuals experienced […]
Read more
$14,145 ASF has been aggressive in funding a number of investigators, as well as multiple centers, involved in providing dietary supplements aimed at augmenting the biological availability of methyl groups (see Beaudet study, in 2000). This project helped facilitate clinical […]
Read more $11,541 Funds for this project built on earlier work by Dr. Calculator (above) and provided additional behavioral treatment strategies to improve communication through nonverbal methodologies.
Read more