Joseph Wagstaff University of Virginia, Charlottesville, VA
2002
Role of the UBE3A Gene Product in Brain Protein Metabolism
$45,547
Dr. Wagstaff was one of the crucial investigators who discovered that UBE3A disruption was the cause of AS. With funds from this and other projects he was able to develop a mouse model for AS and this important development provided a mechanism to learn more about associated proteins in the brain and how proteins change in the brain when UBE3A is disrupted.