$25,000 About 90% of individuals believed to have AS will have abnormal genetic tests that identify one of four mechanisms that can disrupt UBE3A function. There are however about 10% of individuals with apparent AS who have negative genetic testing […]
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$26,000 Funds for this project represent continued funding for this investigator to conduct expanded clinical trials to attempt to demonstrate the effect of providing methylation-rich dietary supplements to those with AS.
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$47,000 For educational planning, it is important to know that children with AS can be effective learners and to understand how this learning occurs under simple paradigms of behavioral modification and analysis. Jane Summers’ work has been instrumental in documenting […]
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$31,300 Individuals with AS lack expressive speech and they have difficulty in understanding the structure and complexity of language. This grant provided funding for a project combining intensive behavioral analysis in combination with visual prompts of alphabet letters, numbers, colors […]
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$31,087 One of the problems in obtaining optimal educational services for children with AS is that there is not much information regarding placement in inclusive classrooms and in other settings. What can we learn from parents and teachers about their […]
Read more $30,000 The work related to this grant extended the long term interest of Dr. Summers in studying how individuals with AS learn and how their behaviors change based on carefully designed behavioral analysis methods in a structured environment. Most importantly, […]
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$85,000 It is known from brain MRI study that there are no obvious malformations associated with AS. However, it is not known if there are more subtle differences in brain development that might provide clues to the action of UBE3A […]
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$58,256 It is known that individuals with AS have an abnormal EEG during periods when seizures do not occur as well as when seizures do occur. Although the patterns of EEG abnormalities have been previously described in AS, there has […]
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