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articles and announcements

Categories: Levodopa

January 23, 2020

Explore the therapeutic potential of levodopa to treat Angelman syndrome in mouse model

$50,000 There is a small amount of anecdotal experience and some neuroscience studies suggesting that levodopa might have therapeutic effect on the symptoms of AS. The Angelman mouse model is an ideal way to study this before developing any human […]

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December 22, 2019

Therapeutic effectiveness of levodopa in the treatment of seizures and motor defects using the Angelman Syndrome mouse model

$50,000 This grant supported a trial of levodopa-carbidopa treatment on AS mice. Levodopa is a dopamine precursor that is converted to dopamine in the brain and is commonly used as a treatment for Parkinson disease. AS mice and normal controls […]

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December 22, 2019

Levodopa/carbidopa treatment of children with Angelman Syndrome

$72,855 ASF has previously supported work at understanding if levodopa might have a potential therapeutic role in AS. This grant provides partial support to a larger clinical trial study which is aimed at implementing a controlled trial of levodopa supplementation […]

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The mission of the Angelman Syndrome Foundation is to advance the awareness and treatment of Angelman syndrome through education and information, research, and support for individuals with Angelman syndrome, their families and other concerned parties. We exist to give all of them a reason to smile, with the ultimate goal of finding a cure.

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