Motor deficits – Angelman Syndrome Foundation

October 10, 2022

Pilot Study to Understand Skilled Motor Impairments in Angelman Syndrome

$200,000 Motor deficits are common and debilitating, but not well-understood, symptoms of Angelman syndrome. AS results from the loss of the UBE3A gene. The development and study of animal models of AS that lack the same gene has advanced our […]

February 18, 2020

Developmental Ube3a effects on language-related assessments in a mouse AS model

Dr. Fitch’s lab has found that the Angelman syndrome mouse model has fewer vocalizations (communication) than typically developing mice. This project proposes to find the brain circuitry responsible for the reduced communication in mice. Preliminary studies suggest it is probably […]

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Categories: Motor deficits

Pilot Study to Understand Skilled Motor Impairments in Angelman Syndrome

Developmental Ube3a effects on language-related assessments in a mouse AS model