Movement disorders significantly impact the daily lives of individuals with Angelman syndrome, including dystonia, tremors, stereotypies, and other poorly understood or unclassified movements. These disorders interfere with regular activities and require better characterization and classification to develop effective treatments. To […]
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$103,000 As individuals with Angelman syndrome get older, there is often an increase in the frequency of abnormal movements, including nonepileptic myoclonus. The goal of this study is to better characterize these abnormal movements to help us identify new ways […]
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$50,000 There is a small amount of anecdotal experience and some neuroscience studies suggesting that levodopa might have therapeutic effect on the symptoms of AS. The Angelman mouse model is an ideal way to study this before developing any human […]
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