Current Research Studies

Nerve Function Study at Massachusetts General Hospital in Boston

Nerve Function Study at Massachusetts General Hospital in Boston

Enrolling participants with AS

The study is enrolling participants with AS between the ages of 4 – 12 to visit Massachusetts General Hospital (MGH) in Boston to conduct a nerve function study. Here’s how it will work:

  • One visit for a nerve conduction test of two nerves in the lower leg.
  • Sensors placed on the lower leg will monitor a small electrical impulse that will run through the two nerves to test their speed, strength and reaction time. Participants may experience mild discomfort with the electrical impulses during the study.
  • Travel costs are the responsibility of the family.

If you would like to enroll your child in this study, contact Olivia Grocott at MGH at or (617) 726-6540.

Your loved one’s participation will help in furthering research and future clinical trials to develop possible treatments for AS! The purpose of this study is measure nerve conduction in the legs to determine if this is a possible biomarker for AS clinical trials. If it proves to be a viable biomarker, then it will help determine if treatments used in future clinical trials are working.

This study is one part of ASF-funded research for a proposal titled Validation of biomarkers for Angelman syndrome clinical trials that is being conducted by Dr. Philpot at UNC, Dr. Thibert at MGH, and Dr. Hazlett at the Carolina Institute of Developmental Disabilities.

The Angelman Syndrome Foundation does not endorse any clinical trial or study, but provides information to the AS community for its own consideration.