Dr. Joseph Wagstaff Boston Children’s Hospital
Melatonin and Sleep in Angelman Syndrome
This research grant determined if melatonin, a well-known drug that has been used to improve sleep, could be effective in individuals with Angelman syndrome (AS). Children with AS were monitored at night using motion detecting devices and sleep observations. This study showed positive results and its findings helped lead to the established therapeutic use of melatonin to help improve sleep in AS.