Angelman Syndrome Research Proposals

Call for Proposals

Special Call for Research to Address Gastrointestinal Complications

There is a special call for research focused on gastrointestinal complications in Angelman syndrome.

Award Amount: up to $100,000
Proposal deadline is March 15, 2021. 


When submitting:

Subject line to read:
ASF MM_20XX Gastro RFP Submission (e.g., ASF 03_2021 Gastro RFP Submission)

File name to read:
PI’s last name_MM_20XX_Gastro_RFP.pdf. (e.g., Smith_03_2021_Gastro_RFP.pdf)

See Instructions for Submission below for more information.

General Research Submissions


The Angelman Syndrome Foundation accepts research proposals on a continual basis, with submission deadlines for subsequent review occurring annually on October 15 and April 15.

One- or two-year grants are awarded for various amounts of up to $100,000 per year.

Current Research Priorities

The ASF Scientific Advisory Committee identified the following areas of unmet need in AS research. Priority will be given to the following topics: 

  • Projects studying or correcting the heterozygous effect of non-UBE3A genes in deletion.  
  • Projects studying the potential results of increasing UBE3A after therapies or for some subtypes of AS.
  • Projects studying delivery of therapies and potential for improvement.
  • Symptomatic therapies that impact the daily life of people with Angelman syndrome and their families.

Proposals that do not address these topics are still welcome and will be given full consideration.

When submitting:

Subject line to read:
ASF MM_20XX General RFP Submission (e.g., ASF 4_2021 General RFP Submission)

File name to read:
PI’s last name_MM_20XX_Gen_RFP.pdf. (e.g., Smith_4_2021_Gen_RFP.pdf)

Instructions for Submission 

All proposals, including cover letters, should be submitted in one (1) .pdf file using the ASF Grant Submission Form and include the following:

  • Cover page completed including title of proposal and name of principal investigator
  • One-page summary abstract of proposed research
  • Proposal, including hypothesis, background, research plan, and significance of the proposed research; page limits indicated within application
  • Curriculum vitae of the applicant
  • One-page detailed budget.  Indirect costs of up to 10% will be allowed (to be included in the total budget amount not to exceed $100,000 per year)
  • Proposals involving human or animal subjects must be approved by institutional review boards before funding is released. Please include approval with proposal if possible.

Questions should be directed to ASF Scientific Advisory Chair, Stormy Chamberlain, PhD, at: