Supporting and Advancing Research


Linking Angelman and Dup15q Data for Expanded Research (LADDER), is a strategic collaboration between the Angelman Syndrome Foundation and the Dup15q Alliance.

See a press release for more information.


What is LADDER?

LADDER is a database that brings together information about Angelman and Dup15q syndromes, collected from sources all over the world including:

Gathering this information in one place, creates a higher level of understanding of AS and Dup15q syndromes which increases the potential for future discoveries that will lead to clinical trials and treatments. In addition, we can better understand how development, behavior and clinical needs change over time.

The data in LADDER can be accessed by:

  • Physicians who treat Angelman syndrome
  • Researchers who are working to find treatments and a cure
  • Pharmaceutical partners who are working on drug development projects

How you can contribute

Visit the LADDER website and enroll!

During enrollment, you will be asked questions about your individual. If he/she has participated in a research study or visited a 15q Clinic, some information could already be in LADDER. Your enrollment will help link the information together. 

Plus, completing enrollment in LADDER, will reduce the number of times you will need to fill out the same information  when participating in collaborating research studies or visiting a 15q Clinical Research Network Clinic.

Enrollment only takes about 20 minutes.