Dr. Gentry Patrick University of California, San Diego, San Diego, CA
2006
Elucidating The Function Of The E6AP Ligase At Mammalian CNS Synapses
$50,000
Work from this grant was part of several projects funded by ASF in order to learn more about UBE3A and its relationship to the larger, complex system of protein degradation (called the ubiquitin-proteasome pathway) that is important to all cellular function. Dr. Patrick’s project helped delineate the action of UBE3A-like enzymes in this complex protein degradation pathway.