![Dr. Ype Elgersma](https://www.angelman.org/wp-content/uploads/2019/12/Dr.-Ype-Elgersma-–-Erasmus-MC-Rotterdam-The-Netherlands-186x186.jpg)
February 3, 2023
Individuals with ICD/UPD Mutations Participating in ASO Trials
$99,000 2 years Angelman syndrome (AS) is caused by loss of maternal UBE3A expression. In neurons, paternal UBE3A is silenced by the UBE3A-ATS transcript, resulting in a total loss of UBE3A in AS neurons. Promising preclinical data by the Beaudet […]
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