December 22, 2019

Novel Ube3a Isoform and Angelman Syndrome

$99,425 At the DNA level, UBE3A represents a single region of DNA molecules but when UBE3A makes its proteins multiple different proteins appear and these are termed isoforms. In this project, Dr. Jiang is evaluating some of the shorter protein […]

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Dr. Ype Elgersma
December 14, 2019

Understanding Ube3a Isoforms

$199,650 The UBE3A protein has two variants called isoforms. This information has been known for some time, but only recently, research discovered that these two isoforms of UBE3A travel to different locations in the brain. The research team is applying this new knowledge to […]

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