$26,000 Funds for this project represent continued funding for this investigator to conduct expanded clinical trials to attempt to demonstrate the effect of providing methylation-rich dietary supplements to those with AS.
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$47,000 For educational planning, it is important to know that children with AS can be effective learners and to understand how this learning occurs under simple paradigms of behavioral modification and analysis. Jane Summers’ work has been instrumental in documenting […]
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$56,000 This grant-funded research was to a premier AS researcher who was instrumental in developing a mouse model for AS and who demonstrated that an important enzyme associated with the synapse, CAMKII, was inhibited or partially inactivated in Angelman mice. […]
Read more$50,000 The gene disrupted in AS, UBE3A, is unique because its action is controlled by a remote DNA region that is called the imprinting center(IC). In the normal brain, this IC turns off the UBE3A that the father contributed (on […]
Read more$47,000 This project was continued funding for an important AS investigator to enable his laboratory to work on studies of UBE3A in the mouse model in the hope of developing novel therapeutic initiatives. The experimental approach in this grant was […]
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$31,300 Individuals with AS lack expressive speech and they have difficulty in understanding the structure and complexity of language. This grant provided funding for a project combining intensive behavioral analysis in combination with visual prompts of alphabet letters, numbers, colors […]
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$30,000 This study evaluated individuals with AS to learn more about contractility of the stomach as measured by surface electrical recordings from the abdominal area. The study provides insight into how the stomach contracts before, during and after ingestion of […]
Read more$82,255 This grant continued ASF funding to one of the premier AS scientists, Dr. Joe Wagstaff, and his laboratory. The aim of this project was a bold attempt to create therapeutic effects in the mouse model by genetically engineering a […]
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