Current Research Studies

Brain Imaging Study

Brain Imaging Study

UNC School of Medicine is conducting multiple Brain Imaging Studies

UNC School of Medicine

Children from 0 to 24 months of age

The goal of the study is to identify the earliest brain and behavioral symptoms of AS, to enable the possibility of detecting early biomarkers and therapeutic targets for potential clinical trials.  Participants will have a non-invasive MRI brain scan during natural sleep (no anesthesia or sedation), behavioral testing, EEG, sleep measures, and physical exam at each visit.


  • Diagnosed with Angelman syndrome, any genotype
  • Currently under 24 months of age
  • First visit at UNC from 0 to 12 mo, depending on age at enrollment
  • Second visit at UNC at 24 months

Participants receive copies of all completed tests. Plus, all travel costs are covered (airfare, hotel, rental car, gas/mileage, meals) and $200 compensation.

See a flyer for the infant study


What is MRI?

MRI (or Magnetic Resonance Imaging) is a medical technology used to view the inside of the body without using X-rays or radiation. MRI can produce detailed 3D images of the brain, which is safe and painless.

Have questions or want to enroll your child?

To enroll or get more information, contact Zumin Chen at (email is best/quickest) or 919-966-8032.

Visit the Shen Lab website 


The Angelman Syndrome Foundation does not endorse any clinical trial or study, but provides information to the AS community for its own consideration.